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Performance Assessment of Blood Screening Assays: Early Dynamics of Hepatitis B Virus (HBV)-DNA and Surface Antigen (HBsAg) in Ramp-Up Phase of Viremia

Performance Assessment of Blood Screening Assays: Early Dynamics of Hepatitis B Virus (HBV)-DNA and Surface Antigen (HBsAg) in Ramp-Up Phase of Viremia

In one of our previous articles, we talked about Hepatitis C, a serious liver disease caused by the hepatitis C virus (HCV) and exposed the severity of HCV and HIV co-infection. Today we discuss Hepatitis B, also a liver infection that is caused by the hepatitis B virus (HBV). Hepatitis B is a viral infection…

An Overview of Monoclonal Antibodies and its Applications

An Overview of Monoclonal Antibodies and its Applications

Antibodies or immunoglobulins (Ig) are glycoproteins generated by differentiated B lymphocytes called plasma cells in response to susceptibility to antigens. The diversity of antibody responses to various target antigens is because of the gene recombination process in the hyper-variable areas of antibodies.  Throughout the recombination technique in their genes, antibodies experience gene rearrangement that enables…

What are the different types of Nucleic Acid Extraction Techniques in molecular diagnostics? 

What are the different types of Nucleic Acid Extraction Techniques in molecular diagnostics? 

In 1953, an important discovery of the double helix structure of deoxyribonucleic acid (DNA) by James Watson, Rosalind Franklin and Francis Crick made huge waves in medical science. The study of DNA structure has since inspired many advancements in genetic science, especially in the field of molecular diagnostics or testing.  Over two decades, the study…

Serum or Plasma: What are their uses, and which is better for research purposes? 

Serum or Plasma: What are their uses, and which is better for research purposes? 

Blood and serum are two of the most essential components of blood. While both comprise the liquid elements of the connective tissue that is blood, they differ in many ways and have various applications in medical research.    We know that blood extraction and collection is a common routine, one which enables us to:     understand and…